Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension?

Table 1

Weight and hematocrit in rats exposed to normoxia (NX), chronic intermittent hypoxia (CIH2x2), and chronic hypoxia (CH) at day 0 (baseline) and day 30 (after exposure). Data are expressed as means ± standard error (SE), and differences were obtained by repeated measures ANOVA; ; compared with the baseline.

	NX		CIH2x2		CH
	Baseline	After exposure	Baseline	After exposure	Baseline	After exposure
Weight (g)	229.5 ± 19.7	226.0 ± 14.2	226.3 ± 25.1	191.0 ± 17.4	228.7 ± 33.9	178.2 ± 20.2
Hematocrit (%)	40.3 ± 1.6	42.4 ± 2.0	39.2 ± 2.5	53.7 ± 3.7	39.2 ± 3.0	63.5 ± 4.2