Diagnostic Yield of Combined Pulmonary Cryobiopsies and Electromagnetic Navigation in Small Pulmonary Nodules

Table 2

Comparison between TBB and TBLC in 29 patients in whom both TBLC and TBB were obtained.

	TBB	TBLC	p value
Sample size (mm)	1.1 ± 0.6	5.3 ± 0.7	<0.001
Diagnostic yield	38 % (11/29)	69 % (20/29)	0.017
Sensitivity	35%	61%	0.008
Specificity	100%	100%	>0.999
Positive PV	100%	100%	>0.999
Negative PV	29%	40%	0.277
Bleeding
Grade 1	7%	38%	0.005
Grade 2	0%	14%	0.043
Grade 3	0%	0%	>0.999

Note: abbreviations: TBB = transbronchial biopsy; TBLC = transbronchial lung cryobiopsy; PV = predictive value. : diagnosis was obtained by TBLC alone in 9 patients and by both TBB and TBLC in 11 patients.