iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice

Figure 5

TGF-β expression: this figure represents the mean and SEM values of TGF-β expression in both peribronchiolar (a) and alveolar (b) wall. The ROFA instillations increased the number of TGF-β-positive cells in both airways and alveolar wall and iNOS inhibition reduced this response only in airways. p<0.05 compared with saline groups; p<0.05 compared with animals that received ROFA and vehicle treatment.

(a)

(b)