Research Article

Correlation between Reduced FEF25-75% and a Positive Methacholine Challenge Test in Adults with Nonobstructive Baseline Spirometry

Table 1

Baseline characteristics and results.

TotalPositiveNegative value

496187 (38%)309 (62%)
Male18658 (31%)128 (69%)
Female310129 (42%)181 (58%)
Age<0.001
BMI0.169
FEF25-75% (L/s)0.003
FEF25-75% (percentage of predicted)<0.001
FEV1/FVC0.019
Prebronchodilator FEV10.367
FEV1% predicted0.064

Results shown as (%) and .