Review Article

Role of the Peroxisome Proliferator-Activated Receptors, Adenosine Monophosphate-Activated Kinase, and Adiponectin in the Ovary

Table 1

Location of PPARs, AMPK, and adiponectin in ovary.

SpeciesLocationmRNA or ProteinReferences

PPAR RatTheca and stroma[52]

PPAR / RatThroughout the ovary[52]

PPAR Mouse, rat, pig, sheep, cow, and humanGranulosa, corpus, luteum, porcine theca and granulosa cells oocytesReviewed by [23]

AMPKRat, cow, chicken, pig, mouseGranulosa cells, oocyte, corpus luteum (weaker in rat theca cells for AMPK 1)mRNA and protein[60ā€“64]

AdiponectinRat, chicken, pigTheca cells, oocyte, and corpus luteum, Follicular liquidmRNA (chicken) mRNA and protein (rat)[12, 13, 51]

Adiponectin receptor IRat, chicken, pigGranulosa and theca cells, oocyte and corpus luteum (rat)mRNA (chicken) mRNA and protein (rat)[12, 13, 51]

Adiponectin receptor IIRat, chicken, pigGranulosa cells, oocyte and corpus luteum (rat)mRNA (chicken) mRNA and protein (rat)[12, 13, 51]