Cardiac PPAR𝛼 Protein Expression is Constant as Alternate Nuclear Receptors and PGC-1 Coordinately Increase During the Postnatal Metabolic Transition

Figure 2

Cytochrome c oxidase 3 expression serves a reporter for the mitochondrial genome (MTCO3; Cytochrome c oxidase polypeptide 3; E.C. 1.9.3.1). MTCO3 increased transiently in the newborn (^**𝑃<.01, versus F & C). Coordinate changes in protein content occurred for PGC-1α, implicated as a regulator of mitochondrial biogenesis.

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