PPAR Research / 2008 / Article / Fig 6

Research Article

Statins Activate Human PPAR 𝛼 Promoter and Increase PPAR 𝛼 mRNA Expression and Activation in HepG2 Cells

Figure 6

The Western blots represent HNF-4 levels in nuclear fractions of HepG2 cells after treatment with atorvastatin (Ator), cerivastatin (Ceri), fluvastatin (Flu), pitavastatin (Pita), pravastatin (Pra), rosuvastatin (Rosu), and simvastatin (Sim) for 24 hours. Each statin was used at doses of 10 (a) or 25 (b) . Nontreated cells (statin concentration ) were the control. HNF-4 protein levels were quantified with an imaging analyzer. The data are expressed as % of control. Values are presented as the mean SEM of three separate experiments, significantly different from control at , .

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