Hexarelin promotes mitochondrial
activity in adipocytes. Scheme of gene expression analysis of fatty acid metabolic regulators in 3T3-L1 adipocytes. Shown are a subset
of genes identified as upregulated (red) or downregulated (green) by hexarelin
compared to untreated cells. These effects of hexarelin require CD36 which is
expressed in adipocytes as opposed to GHS-R1a receptor; FAO, fatty acid
oxidation; FABP, fatty acid binding protein; FAS, fatty acid synthase; HSL,
hormone-sensitive lipase; ACO, acyl CoA oxidase; ACS, and acyl CoA synthase.
Other abbreviations appear in text.
