PPAR Research / 2008 / Article / Fig 1

Review Article

The Development of INT131 as a Selective PPAR 𝜸 Modulator: Approach to a Safer Insulin Sensitizer

Figure 1

Spectrum of PPARγ effects. The range of biological activities, both desired antidiabetic therapeutic effects and undesired effects related to tolerability and safety issues, increases for ligands characterized as antagonists, selective agonists, full agonists, and broad selectivity full agonists.
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