PPAR Research / 2008 / Article / Fig 5

Review Article

The Development of INT131 as a Selective PPAR 𝜸 Modulator: Approach to a Safer Insulin Sensitizer

Figure 5

PPARγ activation by INT131 is cell-type-dependent. Cell-based reporter assays were performed by transfecting three different cell types (HEK293, CV-1, CHO) with the same reporter construct and stimulating with increasing concentrations of rosiglitazone (black) or INT131 (red). Adapted from [17].