The Development of INT131 as a Selective PPAR Modulator: Approach to a Safer Insulin Sensitizer
Figure 6
Glucose level in
Zuker fatty rat is reduced
in response to either INT131 or rosiglitazone treatment. Fourteen-day treatment with the indicated
daily oral dose of INT131 or rosiglitazone
in increasing doses reduce glucose levels. Adapted from
[17, 19].