The Development of INT131 as a Selective PPAR Modulator: Approach to a Safer Insulin Sensitizer
levels increase in a dose responsive manner following either INT131 or
rosiglitazone treatment. Zucker fatty rats were treated orally with the
indicated dose of INT131 or rosiglitazone once daily for 15 days, and plasma
adiponectin was measured. compared to vehicle group adapted from [17, 19].