Effects of Chronic PPAR-Agonist Treatment on Cardiac Structure and Function, Blood Pressure, and Kidney in Healthy Sprague-Dawley Rats

Figure 2

Plasma adiponectin (a) and serum glucose (b) levels in normal male SD rats chronically treated with vehicle (VEH), PD168 at a dose of 10 (PD-10) or 50 mg/kg⋅body weight (PD-50), (𝑛=10/treatment group). Means were compared using one-way ANOVA followed by the Holm-Sidak multiple comparisons test. Data were represented as means ± SEM. Bars designated with “A” are significantly greater in value than bars designated with “B” and so forth (by Holm-Sidak). 𝑝<0.05 was considered significant.

(a)

(b)