The PPAR Ligand GW501516 Reduces Growth but Not Apoptosis in Mouse Inner Medullary Collecting Duct Cells
Figure 6
GW501516 causes a decrease in
protein synthesis at high doses. Serum-starved cells were stimulated for 24 hours with serum-free media (control)
or increasing concentrations of GW501516 ( to M) -leucine
was added to IMCD-K2 cells while they were being stimulated and leucine
incorporation was measured in counts per minute using a scintillation counter,
and expressed as fold control. Values are mean S.E.M.; . compared
to control.
