Fasting Upregulates PPAR Target Genes in Brain and Influences Pituitary Hormone Expression in a PPAR Dependent Manner
Figure 2
Effect of fasting or clofibrate treatment on mRNA concentration of acyl-CoA oxidase (ACO), carnitine palmitoyltransferases (CPT)-1A, medium chain acyl-CoA dehydrogenase (MCAD), long chain acyl-CoA dehydrogenase (LCAD), mitochondrial 3-hydroxy-3-methylglutaryl-(mHMG)-CoA synthase, and peroxisome proliferator-activated receptor (PPAR)- in the liver of rats. All rats obtained a standard basal diet for 4 days. Animals of the fasting group were fasted 36ā€‰hours before killing. Rats of the clofibrate group were treated orally with 250ā€‰mg/kg of clofibrate per day. Values are means (). Symbols indicate significant difference from control rats (, ).
