Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPAR and Identification of TUSC5 Coding Variants in Lean and Obese Humans
Figure 5
Adipose Tusc5 Transcript Levels are not Significantly Altered in Obese Adult Women. Samples from a cohort of obese () and non-obese () women [15] were used to assay mRNA abundance for Tusc5 by quantitative RT-PCR in subcutaneous (SC) and visceral (omental) WAT. Means SEM are depicted, with non-obese SC mRNA levels considered 100%. There were no significant effects of obesity, but depot () and depot x obesity interaction () were observed due to the significantly lower Tusc5 expression in the visceral versus subcutaneous WAT of nonobese volunteers (**).
