Peroxisome Proliferator-Activated Receptor -β/δ, -γ Agonists and Resveratrol Modulate Hypoxia Induced Changes in Nuclear Receptor Activators of Muscle Oxidative Metabolism
Figure 7
The effect of SIRT1 modulator (Resveratrol, 50 μM) treatment for 24 hours, following 7 days of differentiation under relative oxygen regimes, 21%, 5%, and 1%. Fold expression of SIRT1 (a), RXR-α (b) PPAR-α (c), PPAR-γ (d), and CPT-1b (e) mRNA with (+) and without (−) Resveratrol. Values represent the mean of 4-5 experiments. . The effect of Resveratrol within each oxygen regime was evaluated by Students -test within oxygen regime, *, **.
