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PPAR Research
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2010
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Article
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Tab 3
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Research Article
Pioglitazone Attenuates Cystic Burden in the PCK Rodent Model of Polycystic Kidney Disease
Table 3
Serum profiles from PCK female mice—20 mg/kg BW Pioglitazone weeks 4–18.
Normal range
Control diet
Pio diet
-value and significance
Na
+
mM
141–148
.442
NS
K
+
mM
4.3–5.9
.687
NS
Cl
−
mM
101–108
.357
NS
Calcium mg/dl
9.6–11.2
.060
NS
BUN mg/dL
11–17
.118
NS
Creatinine mg/dL
0.4–0.7
.754
NS
Glucose mg/dL
120–186
.055
NS
Alkaline phos. U/L
65–117
.060
NS
Alanine aminotransferase U/L
25–45
.171
NS
Asparagine aminotransferase U/L
72–116
.302
NS
Bilirubin mg/dL
0.2–2
.281
NS
Total protein gr/dL
6.4–7.5
.486
NS
Albumin gr/dL
3.5–5.3
.0001
S
Values are given as means
SEM. Control: PCK rats on the control diet; PIO: PCK rats on a diet containing 20 mg/kg body weight pioglitazone.
: number of animals
-values greater than .05 were considered nonsignificant (NS).