Developmental Effects of Perfluorononanoic Acid in the Mouse Are Dependent on Peroxisome Proliferator-Activated Receptor-Alpha
Figure 1
Effects of prenatal exposure to PFNA on survival of wild-type (WT) and PPARα knockout (KO) mouse pups. Data represent litter means SEM of the percent of the litter alive on postnatal days 0–3, 7, 10, 14, 17, and 21. Survival was reduced in WT pups by 1.1 and 2.0 mg/kg PFNA on GDs 1–18. Asterisks denote a significant difference () found by ANOVA and Bonferroni’s test for multiple comparisons. PND: postnatal day.
