Developmental Effects of Perfluorononanoic Acid in the Mouse Are Dependent on Peroxisome Proliferator-Activated Receptor-Alpha
Figure 3
Effects of prenatal exposure to PFNA on postnatal body weights of wild-type (a, b) and PPARα knockout (c, d) male (a, c) and female (b, d) pups. Data represent litter means ± SEM on postnatal days 0–3, 7, 10, 14, 17, and 21. Body weights of WT pups were reduced by 2 mg/kg PFNA on postnatal days 7, 10, and 14, in male pups and days 7–21 in females. No effect on body weight was found in KO pups. Significant differences were found by ANOVA, and differences between groups were found by Bonferroni’s test for multiple comparisons. Asterisks denote a significant difference ( by t-test, , ).
