Molecular Characterization of the Onset and Progression of Colitis in Inoculated Interleukin-10 Gene-Deficient Mice: A Role for PPAR𝛼

Figure 1

Total histological injury score for duodenum, jejunum, ileum, and colon sections of Il10^−/− and C57 mice at 7, 8.5, 10, 12, and 14 weeks of age. The individual scores and the average score (—) of each sampling group are shown. Statistical analysis was performed only for total colon HIS of Il10^−/− mice and different letters mean that total colon HIS differs compared to 7-week-old Il10^−/− mice (a, b, 𝑃<0.05 and c, 0.05<𝑃<0.1).

(a)

(b)

(c)

(d)