Research Article

Regulation of Proteome Maintenance Gene Expression by Activators of Peroxisome Proliferator-Activated Receptor α

Figure 6

Comparison of the expression of the PM genes after exposure to PPARα, CAR and PXR activators. Lists of differentially regulated genes were generated after exposure to phenobarbital (PB), pregnenolone-16alpha-carbonitrile (PCN) or the PPC. The expression of the PM genes (probe sets) were compared between the treatments. (a) Overlap in the PM gene probesets that were altered in one or more of the three time points after PB or PCN exposure or after 3 or 4 of the 4 PPC treatment groups are shown. (b) The 47 overlapping gene probe sets were clustered as described above.