Gene Expression Profiling in Wild-Type and PPAR𝛼-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPAR𝛼-Independent Effects

Table 1

Average body weight and liver weight of control and PFOS-treated mice on the day of tissue collection${.}^1$

Dose group	WT			Null
	Body weight	Total liver weight	Relative liver weight	Body weight	Total liver weight	Relative liver weight
0 mg/kg	28.3 ± .0	1.21 ± 0.17	0.043 ± 0.014	30.3 ± 1.3	1.04 ± 0.06	0.034 ± 0.003
3 mg/kg	26.2 ± 1.5	1.12 ± 0.18	0.043 ± 0.002	28.0 ± 1.2	1.20 ± 0.05	0.043 ± 0.001
10 mg/kg	31.4 ± 1.5	1.98 ± 0.11*	0.062 ± 0.003*	30.2 ± 1.7	1.48 ± 0.16*	0.049 ± 0.012*

¹Data are mean ± SE, *Significantly different than control ($P\le .05$).