Table 10: Average fold change for genes related to ribosome biogenesis following a seven-day exposure to Wy-14,6431, PFOA1, or PFOS in wild-type and PPARα-null male mice.

WTNull
SymbolGene nameEntrez no.Wy14,643 50 mg/kgPFOA 3 mg/kgPFOS 3 mg/kgPFOS 10 mg/kgPFOA 3 mg/kgPFOS 3 mg/kgPFOS 10 mg/kg

MRPL12mitochondrial
ribosomal protein L12
56282−1.161.251.071.14*−1.16−1.18−1.12*
MRPL13mitochondrial
ribosomal protein L13
685371.321.331.121.35*1.01−1.21−1.42**
MRPL17mitochondrial
ribosomal protein L17
273971.681.761.101.43**1.13−1.131.09
MRPL23mitochondrial
ribosomal protein L23
19935−1.14−1.04−1.001.101.09−1.38−1.20*
MRPL33mitochondrial
ribosomal protein L33
668451.221.261.071.051.04−1.29−1.28**
MRPS12mitochondrial
ribosomal protein S12
24030−1.241.181.051.121.02−1.27−1.15
MRPS18Amitochondrial
ribosomal protein S18A
68565−1.461.341.041.28*1.60−1.19−1.06
RPL10ribosomal protein
L10
110954−1.15−1.211.021.031.07−1.10−1.02
RPL10Aribosomal protein
L10A
19896−1.111.101.031.051.00−1.071.01
RPL11ribosomal protein
L11
670251.141.121.101.11*1.15−1.15−1.09
RPL12ribosomal protein
L12
2692611.011.371.081.15*1.11−1.081.05
RPL13Aribosomal protein
L13a
22121−1.141.031.071.12*−1.17−1.15−1.10
RPL14ribosomal protein
L14
67115−1.28−1.061.151.23**−1.13−1.18−1.22*
RPL17ribosomal protein
L17
319195−1.271.151.031.12−1.52−1.10−1.09
RPL18ribosomal protein
L18
19899−1.111.281.041.07*1.19−1.27−1.09*
RPL18Aribosomal protein
L18a
768081.65−1.371.041.11*1.08−1.15−1.02
RPL19ribosomal protein
L19
199211.221.231.011.051.07−1.11−1.03
RPL21ribosomal protein
L21
199332.001.551.031.091.18−1.20−1.18
RPL22ribosomal protein
L22
199341.171.451.061.29**1.08−1.25−1.14*
RPL23ribosomal protein
L23
65019−1.071.351.061.061.22−1.24−1.16
RPL24ribosomal protein
L24
68193−1.131.071.061.09*−1.00−1.19−1.11*
RPL26ribosomal protein
L26
199411.041.221.031.031.07−1.22−1.18**
RPL27ribosomal protein
L27
199421.04−1.011.081.38**1.06−1.25−1.40*
RPL27Aribosomal protein
L27a
26451−1.071.07−1.001.171.26−1.17−1.09
RPL28ribosomal protein
L28
199431.291.041.011.11*1.67−1.22−1.10
RPL29ribosomal protein
L29
199441.16−1.301.041.091.08−1.23−1.17
RPL3ribosomal protein
L3
27367−1.00−1.141.011.09−1.01−1.031.06
RPL30ribosomal protein
L30
19946−1.15−1.071.02−1.21−1.04−1.29−1.23**
RPL31ribosomal protein
L31
1146411.111.371.091.051.29−1.18−1.12*
RPL32ribosomal protein
L32
199511.061.111.021.12*1.08−1.16−1.03
RPL34ribosomal protein
L34
68436−1.261.16−1.071.05−1.04−1.22−1.31**
RPL35ribosomal protein
L35
66489−1.031.151.131.26**1.04−1.17−1.11
RPL36ribosomal protein
L36
54217−1.071.121.091.23*1.07−1.27−1.20*
RPL37ribosomal protein
L37
67281−1.16−1.181.041.27*1.17−1.19−1.10**
RPL37Aribosomal protein
L37a
19981−1.15−1.091.031.16−1.12−1.22−1.19*
RPL38ribosomal protein
L38
67671−1.171.14−1.011.06−1.03−1.18−1.10
RPL39ribosomal protein
L39
672481.041.021.061.13*1.07−1.18−1.16**
RPL4ribosomal protein
L4
678911.161.431.031.031.321.031.04
RPL41ribosomal protein
L41
67945−1.061.141.051.06−1.13−1.20−1.26*
RPL5ribosomal protein
L5
19983−1.211.021.241.09*−1.05−1.05−1.11
RPL6ribosomal protein
L6
199881.01−1.081.001.051.15−1.051.03
RPL7Aribosomal protein
L7a
27176−1.02−1.111.011.01−1.02−1.071.01
RPL9ribosomal protein
L9
20005−1.35−1.081.031.07−1.11−1.19−1.12*
RPS10ribosomal protein
S10
67097−1.021.021.051.071.00−1.17−1.12*
RPS11ribosomal protein
S11
272071.05−1.74−1.011.111.06−1.24−1.14*
RPS12ribosomal protein
S12
200421.161.221.111.191.22−1.21−1.12
RPS13ribosomal protein
S13
68052−1.031.101.071.22*1.11−1.27−1.22*
RPS14ribosomal protein
S14
20044−1.031.191.051.11*1.01−1.17−1.11**
RPS15Aribosomal protein
S15a
267019−1.051.051.021.121.02−1.14−1.20
RPS16ribosomal protein
S16
20055−1.091.051.051.07−1.02−1.12−1.07
RPS17ribosomal protein
S17
200681.001.161.04−1.19*1.01−1.19−1.15*
RPS19ribosomal protein
S19
20085−1.071.231.081.19**−1.00−1.14−1.05
RPS2ribosomal protein
S2
16898−1.091.021.041.02−1.16−1.031.04
RPS20ribosomal protein
S20
67427−1.401.211.041.151.25−1.11−1.13
RPS21ribosomal protein
S21
664811.11−1.321.151.381.39−1.32−1.25**
RPS23ribosomal protein
S23
664751.011.04−1.001.041.09−1.21−1.10*
RPS24ribosomal protein
S24
200881.581.621.11−1.29*1.75−1.16−1.19**
RPS25ribosomal protein
S25
75617−1.231.011.091.13*−1.02−1.30−1.17*
RPS26ribosomal protein
S26
273701.321.301.041.16*1.14−1.20−1.08
RPS27Aribosomal protein
S27a
782941.05−1.05−1.001.021.09−1.08−1.05
RPS27Lribosomal protein
S27-like
679411.721.281.071.14*1.19−1.18−1.17*
RPS28ribosomal protein
S28
54127−1.19−1.031.031.06−1.05−1.28−1.17*
RPS29ribosomal protein
S29
20090−1.26−1.05−1.021.01−1.03−1.19−1.20**
RPS3ribosomal protein
S3
27050−1.041.291.031.20*−2.88−1.11−1.06
RPS3Aribosomal protein
S3A
544977−1.18−1.071.02−1.01−1.05−1.10−1.03
RPS5ribosomal protein
S5
20103−1.161.181.061.09*−1.02−1.13−1.00
RPS6ribosomal protein
S6
20104−1.20−1.02−1.201.06−1.02−1.14−1.06*
RPS8ribosomal protein
S8
201161.19−1.051.071.13*1.04−1.29−1.13
RPS9ribosomal protein
S9
76846−1.391.301.051.071.05−1.08−1.04

1From Rosen et al. (2008), *Significantly different than control (P.03),
**Significantly different from control (P.0025).