Gene Expression Profiling in Wild-Type and PPAR𝛼-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPAR𝛼-Independent Effects

Table 2

Number of fully annotated genes altered by PFOS, PFOA¹, or Wy-14,64$3^1$ in wild-type and PPAR$\alpha$-null mice ${(P\le .0025)}^2$.

	PFOS		PFOA	Wy 14,643
	3 mg/kg/day	10 mg/kg/day	3 mg/kg	50 mg/kg/day
Wild-type	81	906	879	902
PPAR$\alpha$-null	630	808	176	10

¹From Rosen et al. (2008), ² Based on Ingenuity Pathways Analysis database.