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| | | | | WT | | | Null | |
Symbol | Gene name | Entrez no. | Wy14,643 50 mg/kg | PFOA 3 mg/kg | PFOS 3 mg/kg | PFOS 10 mg/kg | PFOA 3 mg/kg | PFOS 3 mg/kg | PFOS 10 mg/kg |
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PSMA1 | proteasome unit, alpha type, 1 | 26440 | 1.61 | 1.38 | 1.15 | 1.31* | 1.17 | −1.29 | −1.34 |
PSMA2 | proteasome unit, alpha type, 2 | 19166 | −1.46 | −1.15 | 1.09 | 1.23** | −1.34 | −1.20 | −1.07 |
PSMA3 | proteasome unit, alpha type, 3 | 19167 | 1.33 | 1.22 | 1.12 | 1.14 | 1.28 | −1.13 | −1.17 |
PSMA4 | proteasome unit, alpha type, 4 | 26441 | 1.19 | 1.32 | 1.10 | 1.19* | 1.01 | −1.04 | 1.05 |
PSMA5 | proteasome unit, alpha type, 5 | 26442 | 1.67 | 1.59 | 1.12 | 1.26** | 1.15 | −1.12 | 1.09 |
PSMA6 | proteasome unit, alpha type, 6 | 26443 | 1.20 | 1.29 | 1.14 | 1.24** | 1.06 | −1.14 | −1.06 |
PSMA7 | proteasome unit, alpha type, 7 | 26444 | 1.47 | 1.60 | 1.23 | 1.53** | 1.23 | −1.12 | 1.11 |
PSMB1 | proteasome unit, beta type, 1 | 19170 | 1.09 | 1.29 | 1.07 | 1.28* | 1.04 | −1.17 | 1.13* |
PSMB10 | proteasome unit, beta type, 10 | 19171 | −1.42 | −1.48 | −1.25 | −1.19 | −1.57 | −1.14 | −1.21** |
PSMB2 | proteasome unit, beta type, 2 | 26445 | 1.33 | 1.48 | 1.05 | 1.31** | 1.02 | −1.20 | 1.05 |
PSMB3 | proteasome unit, beta type, 3 | 26446 | 1.22 | 1.47 | 1.21 | 1.36** | 1.04 | −1.37 | −1.20 |
PSMB4 | proteasome unit, beta type, 4 | 19172 | 1.59 | 1.65 | 1.27 | 1.55** | 1.22 | −1.12 | 1.09 |
PSMB5 | proteasome unit, beta type, 5 | 19173 | 1.34 | 1.74 | 1.04 | 1.24** | 1.02 | −1.15 | 1.03 |
PSMB6 | proteasome unit, beta type, 6 | 19175 | 1.54 | 1.83 | 1.08 | 1.24* | 1.19 | −1.23 | −1.09 |
PSMB7 | proteasome unit, beta type, 7 | 19177 | 1.46 | 1.33 | 1.07 | 1.15** | 1.13 | −1.17 | −1.09 |
PSMB8 | proteasome unit, beta type, 8 | 16913 | −1.61 | −2.00 | −1.44 | −1.51 | −1.38 | −1.23 | −1.45** |
PSMB9 | proteasome unit, beta type, 9 | 16912 | 1.24 | −1.12 | −1.31 | −1.09 | −1.10 | −1.11 | −1.30** |
PSMC1 | proteasome 26S unit, ATPase, 1 | 19179 | 1.44 | 1.00 | 1.19 | 1.15* | 1.11 | −1.06 | 1.01 |
PSMC6 | proteasome 26S unit, ATPase, 6 | 67089 | 1.18 | 1.21 | 1.09 | −1.02 | 1.07 | 1.14 | −1.16 |
PSMD1 | proteasome 26S unit, non-ATPase, 1 | 70247 | 1.20 | 1.22 | 1.15 | 1.25** | 1.09 | 1.03 | 1.15 |
PSMD11 | proteasome 26S unit, non-ATPase, 11 | 69077 | 1.56 | 1.38 | 1.09 | 1.26* | −1.17 | 1.16 | 1.32 |
PSMD12 | proteasome 26S unit, non-ATPase, 12 | 66997 | 1.34 | 1.27 | 1.10 | 1.14 | 1.20 | −1.03 | 1.04 |
PSMD13 | proteasome 26S unit, non-ATPase, 13 | 23997 | 1.21 | 1.38 | 1.14 | 1.26* | −1.03 | −1.38 | −1.42** |
PSMD14 | proteasome 26S unit, non-ATPase, 14 | 59029 | −1.39 | −1.42 | 1.17 | 1.31* | 1.31 | 1.01 | 1.17 |
PSMD2 | proteasome 26S unit, non-ATPase, 2 | 21762 | 1.34 | 1.32 | 1.14 | 1.24* | 1.10 | 1.09 | 1.30** |
PSMD3 | proteasome 26S unit, non-ATPase, 3 | 22123 | −1.35 | −1.19 | 1.17 | 1.29* | 1.08 | 1.04 | 1.22* |
PSMD4 | proteasome 26S unit, non-ATPase, 4 | 19185 | 1.31 | 1.92 | 1.19 | 1.38** | 1.03 | −1.07 | 1.17* |
PSMD6 | proteasome 26S unit, non-ATPase, 6 | 66413 | 1.17 | 1.33 | 1.10 | 1.14* | 1.07 | −1.06 | 1.04 |
PSMD7 | proteasome 26S unit, non-ATPase, 7 | 17463 | 1.13 | 1.27 | 1.13 | 1.24* | 1.02 | −1.19 | −1.22* |
PSMD8 | proteasome 26S unit, non-ATPase, 8 | 57296 | 1.68 | 1.24 | 1.03 | 1.30** | 1.16 | −1.15 | −1.00 |
PSME1 | proteasome activator unit 1 | 19186 | 1.22 | −1.00 | −1.05 | 1.32** | 1.27 | −1.10 | −1.09 |
VCP | valosin−containing protein | 269523 | 1.40 | 1.49 | 1.04 | 1.12 | 1.07 | 1.13 | 1.21** |
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