Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in Mice

Figure 4

Changes in hepatic expression of conventional PPARα target genes by fenofibrate treatment. Open and closed bars indicate mice treated without or with fenofibrate, respectively. Data are expressed as mean ± SD (𝑛=6/group). *𝑃<0.05; **𝑃<0.01. (a) Analysis of mRNA. Hepatic mRNA levels were normalized to those of GAPDH and then expressed as fold changes relative to levels of Ppara (+/+) mice treated with a control diet. (b) Immunoblot analysis. Band intensities were measured densitometrically, normalized to those of actin, and then expressed as fold changes relative to those of Ppara (+/+) mice treated with a control diet.