The Effect of PPAR Agonists on the Migration of Mature and Immature Eosinophils
Figure 2
The effect on eosinophil chemokinesis of agonists to PPARγ ((a) rosiglitazone), PPARα ((b) GW9578), and PPARδ ((c) GW50516) at low (0.1–100 nM; 9 subjects) and for PPARγ (a; rosiglitazone) at high concentrations (1000–100,000 nM; 6 subjects). Representative pictures at 200x magnification of the leading edge of the nitrocellulose filter after incubation with diluent (d) and 100 nM rosiglitazone (e). Data are shown as mean SEM and expressed as % of the response to diluent.
