Protective Effects of Peroxisome Proliferator-Activated Receptor-α Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes

Figure 4

After 4 h of hepatocellular hypoxia and 10 h of reoxygenation. Effect of hypoxia and reoxygenation on PPARα-mRNA expression in hepatocytes. (Mean ± SD, 𝑛=6) ^c𝑃<0.01 versus control group; ^e𝑃<0.05, ^f𝑃<0.01 versus H/R group. (C: control group; H/R: hypoxia/reoxygenation group; I: Wy14643 group 100 × 10⁻⁶ mol/L; II: Wy14643 group 30 × 10⁻⁶ mol/L; III: Wy14643 group 10 × 10⁻⁶ mol/L; D: DMSO group).

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