Prenatal Rosiglitazone Administration to Neonatal Rat Pups Does Not Alter the Adult Metabolic Phenotype

Table 1

Insulin, glucagon, lipids, and troponin measurements. Plasma samples taken at 20 weeks for metabolic analyses showed there were no significant differences (𝑃>0.05) in insulin, glucagon, lipids, and troponin measurements in RGZ- and dexamethasone-treated groups compared with controls. Values are mean ± SD. 𝑁=24 (6 in each group).

Treatment group	Insulin (ng/mL)	Glucagon (pg/mL)	Triglycerides (mg/dL)	Cholesterol (mg/dL)	Troponin (ng/mL)
Control	2.3±1.7	217.3±12	33.2±15	94.4±15	0.18±0.18
RGZ 0.3 mg/kg	2.6±1.4	190.6±6	35.6±6	105.1±15	0.16±0.23
RGZ 3 mg/kg	2.7±0.9	208.2±23	32.5±23	108.9±14	0.10±0.08
Dexamethasone 0.25 mg/kg	2.3±1.4	207.8±13	30.3±13	95.8±21	0.13±0.13