Peroxisome Proliferator Activated Receptor-α Agonist Slows the Progression of Hypertension, Attenuates Plasma Interleukin-6 Levels and Renal Inflammatory Markers in Angiotensin II Infused Mice

Figure 3

Plasma interleukin-6 levels (𝑛=8 per group) and renal MCP-1 levels (𝑛=5 per group) in control, Ang II-infused and Ang II-infused + fenofibrate-treated WT and PPAR-α KO mice. *indicates a significant increase versus control WT. λ indicates a significant increase versus control PPAR-α KO. ^†indicates a significant increase versus Ang II-infused WT mice. ^≠indicates a significant decrease versus Ang II-infused WT or PPAR-α KO mice.

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