Solution Structures of PPARγ2/RXRα Complexes

Table 1

Structural parameters from SAXS data.

Complexes	𝑅𝑔 (Å)	𝐷max (Å)
PPARγ/RXRα LBD	27.2 ± 0.1	85 ± 5
TIF2 RID/PPARγ/RXRα LBD	35.5 ± 0.1	150 ± 10
TIF2 RID	33 ± 1	130 ± 10
PPARγ2ΔNTD/RXRαΔNTD/PPRE (CYP4A1)	37.1 ± 0.4	140 ± 10
PPARγ2/RXRαΔNTD/PPRE	44 ± 0.5	160 ± 10
PPARγ2/RXRα/PPRE	52 ± 0.5 [16]	180 ± 10 [16]
TIF2 RID/PPARγ2/RXRα/PPRE	59 ± 0.5	200 ± 20