Research Article

Does Pro12Ala Polymorphism Enhance the Physiological Role of PPAR 2?

Table 2

Included studies in the meta-analysis for T2D and respective genotype of the studied population.

StudyPopulation Metabolic 
disorder
ParticipantsNo. of cases 
(D)
No. of control 
(ND)
Genotype
Pro/ProPro/AlaAla/Ala
DNDDNDDND

Ghoussaini et al., 2005 [17]FrenchT2D + RIS9466283185112461136349
Lindi et al., 2002 [21]FinnishT2D490248242163174796167
Chistiakov et al., 2010 [22]RussianT2D + RIS11855885974013531672082036
Oh et al., 2000 [1]KoreanT2D229581715415731410
Bouassida et al., 2005 [23]TunisianT2D488242246216221262302
Malecki et al., 2003 [24]PolishT2D64436627825620299661110
Pintérová et al., 2004 [25]CzechT2D230133979961313036
Mori et al., 2001 [26]JapaneseT2D341322011212209711141039612

Summary762544643161379725286215614672

Legend: T2D: type 2 diabetes mellitus; D: diabetic; ND: non-diabetic; RIS: reduced insulin sensitivity.