The Proatherogenic Effect of Chronic Nitric Oxide Synthesis Inhibition in ApoE-Null Mice Is Dependent on the Presence of PPARα
Figure 3
Aortic NADPH oxidase correlates with Nox1. (a) DKO mice are immune to the significant (*) induction of NDAPH oxidase activity induced by L-NAME in the ApoE-null mice (mice number). (b) Relative expression of Nox1 mRNA (adjusted for actin) in mice aortas (mice numbers), which parallels NADPH oxidase activity, and is significantly correlated to it in a subset of mice in which both measurements were performed (c).
