Modes-of-Action Related to Repeated Dose Toxicity: Tissue-Specific Biological Roles of PPAR<i>γ</i> Ligand-Dependent Dysregulation in Nonalcoholic Fatty Liver Disease

<table>A simplified presentation of the fatty acids transport, metabolism, and fate in the human organism. FAT/CD36: fatty acid translocase/cluster determinant 36; FABPpm: plasma membrane fatty acid binding protein; SLC 27A2: solute carrier family 27 (fatty acid transporter), member 2; SLC 27A5: solute carrier family 27 (fatty acid transporter), member 5; FA: fatty acids; TG: triglycerides; VLDL: very low-density lipoprotein; LPL: lipoprotein lipase; LD: lipid droplet.</table>

PPAR Research

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Figure 1

Figure 1: Modes-of-Action Related to Repeated Dose Toxicity: Tissue-Specific Biological Roles of PPAR<i>γ</i> Ligand-Dependent Dysregulation in Nonalcoholic Fatty Liver Disease 

Figure 1 | Modes-of-Action Related to Repeated Dose Toxicity: Tissue-Specific Biological Roles of PPARγ Ligand-Dependent Dysregulation in Nonalcoholic Fatty Liver Disease 