Effects and Potential Mechanisms of Pioglitazone on Lipid Metabolism in Obese Diabetic KKAy Mice

Figure 2

Effects of pioglitazone on biochemical variables involved in fatty acid metabolism and tissue weight in KKAy mice. The levels of plasma TG (a), plasma FFA (b), plasma levels of AST (c), plasma levels of ALT (d), liver TG (e), and FFA (f) were measured by commercial kits. The final body weight (g), liver weight (h) and WAT weight (i) were recorded at the end of the treatment. Nor, C57BL/6J mice; Con, vehicle-treated KKAy mice; Piog, pioglitazone-treated KKAy mice. Data are presented as mean ± S.E.M. (𝑛=10 per group). *𝑃<0.05, **𝑃<0.01 versus Con.

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