Neuroprotective Potential of Peroxisome Proliferator Activated Receptor-α Agonist in Cognitive Impairment in Parkinson’s Disease: Behavioral, Biochemical, and PBPK Profile

Table 2

The comparison of predicted and in vivo pharmacokinetic parameters of fenofibric acid.

Sr. number	Pharmacokinetic parameters	In vivo	Predicted	Predicted/𝑖𝑛𝑣𝑖𝑣𝑜 ratio
1	AUC0--𝑡 (µg h/mL)	274.68±38.11	271.89	0.99
2	𝐶max (µg/mL)	20.49±2.32	17.58	0.86
3	𝑇max (hours)	3.77±0.64	3	0.80
4	𝑓2 Value	67.37