PPAR Research / 2015 / Article / Fig 4

Research Article

KLF15 and PPARα Cooperate to Regulate Cardiomyocyte Lipid Gene Expression and Oxidation

Figure 4

Ligand induced PPARα gene targets are KLF15 dependent. Fatp1 (a), Pdk4 (b), Slc25a20 (c), Acadm (d), Cpt2 (e), and Cd36 (f) expression (qPCR) in neonatal rat ventricular cardiomyocytes after sh-RNA mediated Klf15 silencing in the absence or presence of the PPARα-specific ligand WY-14,643 (10 μM, 24 hrs). (). versus vehicle. versus sh-KLF15. versus WY-14643. Values normalized to Ppib.

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