PPAR Research / 2015 / Article / Tab 1

Review Article

Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention

Table 1

The proposed targets and effects of TZDs in PT and TAL.

Nephron segmentTargetsSpeciesMaterialsEffectsCitation

PTNBCe1Rat
Rabbit
Human
Isolated proximal tubuleStimulation of transport[12]
PTNHE3Rabbit Isolated proximal tubuleStimulation of activity[12]
PTNHE3Sprague-Dawley ratTotal kidney homogenateEnhancement of protein expression[13]
TALNKCC2Sprague-Dawley ratTotal kidney homogenateEnhancement of protein expression[13]

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