HDAC Inhibition Modulates Cardiac PPARs and Fatty Acid Metabolism in Diabetic Cardiomyopathy

Table 1

Lipid parameters of Wistar, diabetes mellitus (DM), and MPT0E014-treated DM rats.

	WKY	DM	DM + MPT0E104
Cholesterol (mmol/L)	1.4 ± 0.1	2.1 ± 0.1	1.5 ± 0.1
Triglyceride (mmol/L)	1.1 ± 0.2	3.0 ± 0.5	1.0 ± 0.5
HDL-C (mmol/L)	0.3 ± 0.3	0.4 ± 0.4	0.4 ± 0.4
Free fatty acid (mol/L)	17.5 ± 1.7	30.9 ± 3.8	16.8 ± 2.9
Insulin (pmol/L)	141.2 ± 28.3	55.0 ± 10.8	67.2 ± 13.2

HDL-C: high-density lipoprotein-cholesterol. Values are expressed as the mean ± SEM, .   versus Wistar rats, versus DM rats, and versus MPT0E014-treated DM rats.