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PPAR Research
Volume 2016, Article ID 6042162, 6 pages
http://dx.doi.org/10.1155/2016/6042162
Research Article

PPARgene: A Database of Experimentally Verified and Computationally Predicted PPAR Target Genes

1Institute of Cardiovascular Sciences, Peking University Health Science Center, Beijing 100191, China
2Department of Biomedical Informatics, Peking University Health Science Center, Beijing 100191, China
3The Advanced Institute for Medical Sciences, Dalian Medical University, Dalian 116044, China

Received 21 January 2016; Accepted 24 March 2016

Academic Editor: Todd Leff

Copyright © 2016 Li Fang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [22 citations]

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  • Yan-Hui Li, Gai-Gai Zhang, and Nanping Wang, “Systematic Characterization and Prediction of Human Hypertension Genes,” Hypertension, vol. 69, no. 2, pp. 349–355, 2016. View at Publisher · View at Google Scholar
  • Rolf Müller, “PPARβ/δ in human cancer,” Biochimie, 2016. View at Publisher · View at Google Scholar
  • Shlomo Sasson, “4-Hydroxyalkenal-activated PPARδ mediates hormetic interactions in diabetes,” Biochimie, 2016. View at Publisher · View at Google Scholar
  • L Sun, Y Shi, G Wang, X Wang, S Zeng, S E Dunn, G D Fairn, Y-J Li, and D E Spaner, “PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells,” Leukemia, 2017. View at Publisher · View at Google Scholar
  • You-Lin Tain, and Chien-Ning Hsu, “Interplay between Oxidative Stress and Nutrient Sensing Signaling in the Developmental Origins of Cardiovascular Disease,” International Journal of Molecular Sciences, vol. 18, no. 4, pp. 841, 2017. View at Publisher · View at Google Scholar
  • Jing-Ping Lin, Yevgeniya A Mironova, Peter Shrager, and Roman J Giger, “LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair,” eLife, vol. 6, 2017. View at Publisher · View at Google Scholar
  • Xiaohua Hu, Xianjun Shen, Jincai Yang, Chunjie Guo, and Xingpeng Jiang, “Systematic characterization and prediction of tumor-associated genes in mouse using microRNA,” Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017, vol. 2017-, pp. 1338–1344, 2017. View at Publisher · View at Google Scholar
  • Y-J Li, L Sun, Y Shi, G Wang, X Wang, S E Dunn, C Iorio, R A Screaton, and D E Spaner, “PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions,” Leukemia, 2017. View at Publisher · View at Google Scholar
  • Bàrbara Reynés, Mariona Palou, and Andreu Palou, “Gene expression modulation of lipid and central energetic metabolism related genes by high-fat diet intake in the main homeostatic tissues,” Food Funct., 2017. View at Publisher · View at Google Scholar
  • Qinyu Yao, Jia Liu, Zihui Zhang, Fan Li, Chao Zhang, Baochang Lai, Lei Xiao, and Nanping Wang, “ Peroxisome proliferator–activated receptor γ (PPARγ) induces the gene expression of integrin α V β 5 to promote macrophage M2 polarization ,” Journal of Biological Chemistry, vol. 293, no. 43, pp. 16572–16582, 2018. View at Publisher · View at Google Scholar
  • Meiqian Zhang, Zihui Zhang, Xinya Xie, Qinyu Yao, Jia Liu, Baochang Lai, Lei Xiao, and Nanping Wang, “Xenobiotic pregnane X receptor promotes neointimal formation in balloon-injured rat carotid arteries,” Journal of Cellular Physiology, 2018. View at Publisher · View at Google Scholar
  • You-Lin Tain, and Chien-Ning Hsu, “Developmental Programming of the Metabolic Syndrome: Can We Reprogram with Resveratrol?,” International Journal of Molecular Sciences, vol. 19, no. 9, pp. 2584, 2018. View at Publisher · View at Google Scholar
  • Foteini Malliou, Ioanna Andreadou, Frank J. Gonzalez, Antigone Lazou, Eva Xepapadaki, Ioanna Vallianou, George Lambrinidis, Emmanuel Mikros, Marios Marselos, Alexios-Leandros Skaltsounis, and Maria Konstandi, “The olive constituent oleuropein, as a PPARα agonist, reduces markedly serum triglycerides,” The Journal of Nutritional Biochemistry, 2018. View at Publisher · View at Google Scholar
  • Concha Nieto, Rafael Bragado, Cristina Municio, Elena Sierra-Filardi, Bárbara Alonso, María M. Escribese, Jorge Domínguez-Andrés, Carlos Ardavín, Antonio Castrillo, Miguel A. Vega, Amaya Puig-Kröger, and Angel L. Corbí, “The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages,” Frontiers in Immunology, vol. 9, 2018. View at Publisher · View at Google Scholar
  • Saghar Yousefnia, Sara Momenzadeh, Farzad Seyed Forootan, Kamran Ghaedi, and Mohammad Hossein Nasr Esfahani, “The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity,” Gene, 2018. View at Publisher · View at Google Scholar
  • You-Lin Tain, Samuel H.H. Chan, and Julie Y.H. Chan, “Biochemical basis for pharmacological intervention as a reprogramming strategy against hypertension and kidney disease of developmental origin,” Biochemical Pharmacology, 2018. View at Publisher · View at Google Scholar
  • Jia Liu, Qinyu Yao, Lei Xiao, Wen Ma, Fan Li, Baochang Lai, and Nanping Wang, “ PPAR γ induces NEDD 4 gene expression to promote autophagy and insulin action ,” The FEBS Journal, 2019. View at Publisher · View at Google Scholar
  • Virag Vas, Tamás Háhner, Gyöngyi Kudlik, Dávid Ernszt, Krisztián Kvell, Dániel Kuti, Krisztina J. Kovács, József Tóvári, Mária Trexler, Balázs L. Merő, Bálint Szeder, Kitti Koprivanacz, and László Buday, “Analysis of Tks4 Knockout Mice Suggests a Role for Tks4 in Adipose Tissue Homeostasis in the Context of Beigeing,” Cells, vol. 8, no. 8, pp. 831, 2019. View at Publisher · View at Google Scholar
  • Ying Tian, Chunmiao Yang, Qinyu Yao, Lei Qian, Jia Liu, Xinya Xie, Wen Ma, Xin Nie, Baochang Lai, Lei Xiao, and Nanping Wang, “Procyanidin B2 Activates PPARγ to Induce M2 Polarization in Mouse Macrophages,” Frontiers in Immunology, vol. 10, 2019. View at Publisher · View at Google Scholar
  • Zihui Zhang, Xinya Xie, Qinyu Yao, Jia Liu, Ying Tian, Chunmiao Yang, Lei Xiao, and Nanping Wang, “PPARδ agonist prevents endothelial dysfunction via induction of dihydrofolate reductase gene and activation of tetrahydrobiopterin salvage pathway,” British Journal of Pharmacology, 2019. View at Publisher · View at Google Scholar
  • Bahram Namjou, Todd Lingren, Yongbo Huang, Sreeja Parameswaran, Beth L. Cobb, Ian B. Stanaway, John J. Connolly, Frank D. Mentch, Barbara Benoit, Xinnan Niu, Wei-Qi Wei, Robert J. Carroll, Jennifer A. Pacheco, Isaac T. W. Harley, Senad Divanovic, David S. Carrell, Eric B. Larson, David J. Carey, Shefali Verma, Marylyn D. Ritchie, Ali G. Gharavi, Shawn Murphy, Marc S. Williams, David R. Crosslin, Gail P. Jarvik, Iftikhar J. Kullo, Hakon Hakonarson, Rongling Li, Stavra A. Xanthakos, and John B. Harley, “GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network,” BMC Medicine, vol. 17, no. 1, 2019. View at Publisher · View at Google Scholar
  • Caitlyn E. Bowman, Ebru S. Selen Alpergin, Kyle Cavagnini, Danielle M. Smith, Susanna Scafidi, and Michael J. Wolfgang, “Maternal Lipid Metabolism Directs Fetal Liver Programming following Nutrient Stress,” Cell Reports, vol. 29, no. 5, pp. 1299–1310.e3, 2019. View at Publisher · View at Google Scholar