Fenofibrate plus Metformin Produces Cardioprotection in a Type 2 Diabetes and Acute Myocardial Infarction Model

Figure 2

Effect of subchronic treatment (14 days) of different drugs on (a) body weight and (b) nonfasting capillary glucose concentrations of control- (CT-) and diabetic- (DB-) rats. (c) Capillary glucose levels in CT- and DB-rats before and during an oral glucose tolerance test (OGTT) (2 g/kg) after 14 days of subchronic treatment. (d) Area under the curve for OGTT. versus CT, versus CT-vehicle, versus DB-vehicle, versus fenofibrate (Feno, 100 mg/kg), and versus metformin (Metfor, 100 mg/kg) two-way ANOVA followed by Duncan’s post hoc test. Data are presented as means ± SEM of 6 animals per group.

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