Research Article

[Retracted] Possible Role of Interaction between PPARα and Cyclophilin D in Cardioprotection of AMPK against In Vivo Ischemia-Reperfusion in Rats

Figure 6

Effects of SfA, A-769662, or their combination on IR-induced CyP-D-PPARα interaction. Isolated mitochondria were immunoprecipitated (IP) with anti-PPARα (a) or anti-CyP-D (b) antibodies. The complexes were subjected to SDS-PAGE, followed by immunoblotting (IB) with CyP-D (a) or PPARα (b) antibodies. Representative immunoblots (a and b, top panels) show the effects of A-769662 and/or SfA on the interaction between PPARα and CyP-D. Quantitative results (a and b, bottom panels) were expressed as a fold change, compared with Sham. -4 per each group. versus Sham; versus IR.
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