Research Article

Fatty Acids of CLA-Enriched Egg Yolks Can Induce Transcriptional Activation of Peroxisome Proliferator-Activated Receptors in MCF-7 Breast Cancer Cells

Figure 2

Experimental mechanism for studying the activity of EFA-CLA as a ligand for PPAR. DBD: DNA-binding domain specific for PPRE sequence in promoter regions of genes regulated by PPAR; LBD: ligand-binding domain (e.g., EFA-CLA).