MicroRNAs-Dependent Regulation of PPARs in Metabolic Diseases and Cancers

Figure 4

miRNAs expression induced by PPARα and PPARγ. Induction of miRNAs by PPARα (Panel (a)) and PPARγ (Panel (b)) binding to PPRE in pri-miRNA promoters in specific tissues is indicated. miRNAs identified in human studies are in blue, those identified in mouse/rat studies are in green, and those identified in both human and rodents studies are in red. RXR: Retinoid-X-Receptor; Prdm16: PR domain-containing 16; PPRE: peroxisome proliferator response element.

(a)

(b)