Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway

Figure 5

Different functional domains of ANGPTL4. Native full-length ANGPTL4 (flANGPTL4) is present as dimeric or tetrameric complexes. It can be processed to generate the N-terminal coiled-coil fragment (nANGPTL4) and COOH terminal fibrinogen-like domain (cANGPTL4), respectively. These protein fractions seem to have distinct roles depending on the tissue context.