6-Gingerol Normalizes the Expression of Biomarkers Related to Hypertension via PPARδ in HUVECs, HEK293, and Differentiated 3T3-L1 Cells

Figure 6

Oil Red O staining in differentiated 3T3-L1 cells treated with 6-gingerol and GSK0660. (a, b) 6-Gingerol decreased the lipid accumulation in differentiated 3T3-L1 cells compared to differentiation control. In addition, the effect of 6-gingerol was revered by PPARδ antagonist. Magnification is 200 times. The results are expressed as means ± SEM (n=3). Values were statistically analyzed by unpaired t-test. All experiments were repeated three or more times. The statistical significance between the two experimental groups was marked as p < 0.05 and p < 0.001. Meaning of indications: Ctrl means untreated normal control group, D-Ctrl means differentiation control group without treatment, G means 6-gingerol treated group during differentiation, and GG means 6-gingerol and GSK0660 treated group during differentiation.

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