Peroxisome Proliferator-Activated Receptor γ and PGC-1α in Cancer: Dual Actions as Tumor Promoter and Suppressor

Figure 1

Structure of PPARγ (a) and the PGC-1 family (b). (a) A/B, transcriptional activation domain; C, DNA binding domain (DBD); D, hinge region; E/F, ligand binding domain (LBD). (b) AD, transcriptional activation domain; RD, transcriptional repression domain; RS, arginine/serine rich domain; RRM, RNA binding domain.

(a)

(b)