Vascular Remodeling, Oxidative Stress, and Disrupted PPARγ Expression in Rats of Long-Term Hyperhomocysteinemia with Metabolic Disturbance

Table 1

Parameter values in Wistar rats after 48 weeks of treatment with control and methionine-supplemented diets (/group).

Parameters	Control-diet group	Met-diet group
Water intake (ml/d)			0.014
Food intake (g/d)			0.142
Spleen weight/body weight (mg/100 g)			0.001
Fasting blood glucose (mmol/L)			<0.001
Serum triglyceride (mmol/L)			<0.001
Serum total cholesterol (mmol/L)			<0.001
Serum high density lipoprotein (mmol/L)			0.753
Serum low density lipoprotein (mmol/L)			0.423
Serum NO (umol/L)			<0.001
Serum MDA (umol/L)			<0.001
Serum SOD (umol/L)			<0.001
Plasma homocysteine (umol/L)			<0.001

Met, methionine. Data are presented as mean ± SEM. Significantly different from corresponding values in the control group.