PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients

<div>Immunohistochemical detection of CD163+ cells in the psoriatic plaque biopsy specimen before (a) and after treatment with 30 mg pioglitazone (b). CD163+ cells (arrows) are rather tightly represented in the dermal papillae surrounding the vessels. Contrasting: Mayer’s haemalaun, mg, ×400. Scale bars, 0.2 <i>μ</i>m. CD163+ сell number in all groups did not differ significantly before and after treatment (c).</div>

PPAR Research

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Figure 2

Figure 2: PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients 